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What should I discuss with my healthcare provider before taking flutamideEulexin
Other drugs may interact with flutamideincluding prescription and over-the-counter medicinesvitaminsand herbal productsTell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Serum transaminase levels should be measured prior to starting treatment with flutamideFlutamide is not recommended in patients whose ALT values exceed twice the upper limit of normalSerum transaminase levels should then be measured monthly for the first 4 months of therapyand periodically thereafterLiver function tests also should be obtained at the first signs and symptoms suggestive of liver dysfunctionegnauseavomitingabdominal painfatigueanorexiaflu-likesymptomshyperbilirubinuriajaundiceor right upper quadrant tendernessIf at any time a patient has jaundiceor their ALT rises above 2 times the upper limit of normalflutamide should be immediately discontinued with close follow-up of liver function tests until resolution.
Serum transaminase levels should be measured prior to starting treatment with flutamideFlutamide is not recommended in patients whose ALT values exceed twice the upper limit of normalSerum transaminase levels should then be measured monthly for the first 4 months of therapyand periodically thereafterLiver function tests also should be obtained at the first signs and symptoms suggestive of liver dysfunctionegnauseavomitingabdominal painfatigueanorexiaflu-likesymptomshyperbilirubinuriajaundiceor right upper quadrant tendernessIf at any time a patient has jaundiceor their ALT rises above 2 times the upper limit of normalflutamide should be immediately discontinued with close follow-up of liver function tests until resolution.
Flutamide and its metabolites are excreted mainly in the urine with only 4.2of a single dose excreted in the feces over 72 hours.
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