The study showed no real differences in hba1c reductions produced by a combination of sitagliptin and metformin compared to a combination of glipizide glucotrol and metformin.

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Avoid using the extended-release tablets in patients with severe gastrointestinal narrowing of esophageal dysmotility.
Generic NameglipizideGLIP i zideBrand NamesGlucotrolGlucotrol XLGlipiZIDE XL.
Cholestatic jaundice and hepatitis occur rarely but may progress to liver failure.
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vomiting, nausea, appetite loss, constipations, diarrhea, gas, headache, and weight gain are some of the side effects that may arise from using glucotrol xl.
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